Onset and remission of eczema at pre-school age in relation to prenatal and postnatal air pollution and home environment across China

We investigated associations between prenatal and postnatal environmental factors onset remission of preschool childhood eczema across China. The study population was preschoolers in randomized day care centers seven cities (N = 39,782). Data on indoor outdoor environment were obtained from a cross-sectional questionnaire sent to parents or other guardians. Reports the first 2 years past year used retrospectively calculate (changes reported eczema). Prenatal temperature, NO2 PM10 modelled official air pollution data. Associations estimated by two-level logistic regression. Calculated rate 3.2%/y 29.2%/y. Exposure during pregnancy associated with eczema, similarly for all trimesters. Postnatal related decreased remission. temperature eczema. Pre-natal current redecoration buying new furniture, perinatal as well dampness mould, increased Cockroaches home another risk factors. exposure farm large family size negatively In conclusion, warmer climate can be Chinese preschoolers. reduced Perinatal dampness, mould cockroaches may increase decrease chemical emissions materials after life onset. could protective.